Overview
ICSI is used within an IVF cycle when sperm parameters or prior fertilization outcomes suggest that conventional insemination may under-perform. A single sperm is selected and injected into each mature egg.
Common Indications
- Severe or moderate male-factor infertility
- Prior fertilization failure with conventional IVF
- Cryopreserved sperm with limited count
- Surgical sperm retrieval
How It Works
- Standard IVF stimulation and retrieval.
- Embryologist selects individual sperm.
- Each mature egg is injected under microscopy.
- Culture, transfer, and cryopreservation as with standard IVF.
Considerations
- ICSI improves fertilization rate in appropriate cases but does not overcome underlying egg or embryo quality issues.
- Should be used based on documented indication, not as a routine add-on.
Educational content only. No procedure guarantees an outcome. Decisions must be made with a licensed specialist.